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According to NICE guidance and standard UK clinical practice, patients with confirmed B12 deficiency and neurological symptoms typically require initial treatment with hydroxocobalamin injections

Interestingly, TNF-alpha has been shown to interrupt tight junctions, thus worsening any underlying tight junction dysfunction

We well as boost energy levels, improve symptoms of depression, anxiety, and mental clarity/ cognitive function

It is studied for supporting collagen organization, antioxidant and anti-inflammatory signaling, and skin repair processes, and it is widely used in cosmetic science for skin and scalp support